Building World-Changing Businesses

Evoralis specialise in pioneering enzyme development with a mission to revolutionise plastic recycling. Spun out from the Hollfelder Lab at the University of Cambridge, their cutting-edge work focuses on creating biocatalysts that break down plastics, paving the way for a truly circular economy.

Cambridge Electric Cement (CEC), a sustainable cement spin-out from the University of Cambridge, has developed the world’s first process for making low carbon, recycled cement, by processing it through the same electric arc furnaces (EAFs) as those used in steel recycling.

Wave Photonics enable rapid photonic integrated circuit development for any wavelength or platform. The company help new photonics fabrication processes to be rapidly brought online, especially those using novel materials or wavelengths targeting applications in sensing or quantum technologies.

xWatts, a University of Cambridge spin-out, is developing an intelligent energy management software that reduces costs and emissions by 30% in large commercial buildings via autonomation and predictive control. With minimal user intervention, the company’s software automates and controls all isolated processes, such as operations, heating, cooling or storage.

DeepForm‘s novel press tool designs for automotive and other high volume customers, suited to a wide range of steel and aluminium panels. DeepForm’s fold-shear process replaces the draw stage in a conventional cold stamping line-up. In one tool, regions of the part are folded whilst soaking up material in customised 3-D blankholders, before completing the

adsilico is developing an end-to-end in-silico trials solution based on virtual ‘synthetic patient populations that will provide better and safer medical devices earlier to patients, reduce costs and accelerate R&D timescales for medical device developers, contribute to animal welfare by reducing animal experimentation, reducing refining and partially replacing costly and potentially har

Koalaa is developing the next generation of prosthetics and orthotics for people with upper limb differences. The Imperial College London spin-out has designed a range of comfortable, affordable, and functional prosthetics with modular tools that can clip into the sleeve and be used for specific tasks.

Albus Health has developed a passive, contactless home monitoring device that tracks biomarkers such as respiratory rate in patients while they are asleep without disturbing them. The device also captures environmental metrics, such as air quality, humidity and temperature.

MeVitae has developed software to streamline recruitment processes, using data-driven technology to attract, screen and retain top talent whilst building diverse and productive teams fairly. The software aims to eliminate 15 bias parameters using its suite of Artificial Intelligence-based solutions.

Concr is a value-driven techbio company, spun out of the University of Cambridge, applying statistical learning and advanced modelling adopted from astrophysics to aid in the precision treatment of cancer patients. Concr’s online platform allows the storage, management and analysis of data generating actionable insights for cost-effective drug development and patient treatment.

Accelercomm is a leader in high-performance wireless communications solutions. The University of Southampton spin-out has developed patented communications algorithms for 5G, doubling network capacity whilst halving power consumption and slashing latency. Accelercomm’s patent-protected solutions offer a complete physical layer IP solution enabling optimal performance for 5G radio access networks

OSSTEC is an Imperial College spin-out which has developed a bone healing technology to improve patient care from the lab to the operating room. Their additive manufactured bone healing platform technology will look to change orthopaedics by keeping patients healthy and active.

Zomp is a University of Cambridge spin-out which is building the world’s first 3D imaging cytometer and cell sorter. This new 3D imaging cytometry will revolutionise cell sorting and analysis, enabling the accurate measurement and sorting of single cells at high throughput based on observable characteristics.

Signaloid has developed an innovative computing platform for tracking uncertainty in data while executing applications. The Company’s computing platform can achieve this at speeds significantly faster than existing solutions. Signaloid is focusing on a cloud-based deployment of its computing platform, allowing for seamless integration with existing cloud-based data processing workloads.

Enhanc3D Genomics is developing a proprietary technology that simultaneously profiles 3D genome folding at high resolution for all genes and their enhancers. This links gene enhancers and non-coding genetic variants to their target genes.

Crypto Quantique is an Internet of Things (IoT) security company with a mission to revolutionise the IoT with quantum driven cybersecurity. The company provides a dual hardware and software end-to-end solution to current and future cyber security threats to IoT security.

Spirea is developing the next generation of Antibody-Drug Conjugate (ADC) drugs for cancer treatment. The company have designed a novel, wholly owned linker technology to improve ADC efficacy and tolerability. ADCs are drugs that combine both antibody and cytotoxic drugs via a linker molecule to target the tumour cell.

NK:IO is an Imperial spinout developing small molecule and cell-mediated immunotherapy for the treatment ofcancer. The company is developing techniques aimed at increasing the potential of natural killer cells for use inimmunotherapies for cancer. The company is validating its proof of concept studies after many years of work onnatural killer cell biology. It has progressed

SERG Technologies is developing a connected platform which enables remote, patient-specific assessment of all Parkinson’s disease motor symptoms, delivering actionable insights that optimise treatment, promote lifestyle changes thus increasing patient mobility and independence.

Sano Genetics is building a fully personalised software platform that acts as a “virtual Biobank” for genetic data, medical records and other ‘omics data’, enabling rapid and cost-effective recruitment of patients for clinical trials and precision medicine research.

52 North is developing the world’s first finger-prick blood test to provide both a white blood cell count and blood lactate level, enabling rapid triage of chemotherapy patients at risk of life-threatening infections. 52 North is a spin-out from the University of Cambridge.

Diffblue is leading the automation of software creation through the power of AI. Founded by researchers from the University of Oxford, Diffblue Cover uses AI for code to write unit tests that help software teams and organizations efficiently improve their code coverage and quality and to ship software faster, more frequently and with fewer defects.

Semarion is a University of Cambridge spin-out from the Cavendish Laboratory. The company is commercialising their SemaCyte® technology, a platform that revolutionises in-vitro cell handling with applications across drug discovery and life sciences R&D.

Pathfinder Medical is an Imperial spinout MedTech business that has a unique technology to allow surgeons to make connections across blood vessels. There are several applications for this technique, with a key one being for patients with kidney failure who are undergoing dialysis treatment.

Wayland Additive Limited (Wayland) has developed a novel electron beam powder bed fusion process for metal additive manufacturing, which removes some of the technical issues which make the process less efficient and flexible than rival technologies and increases the range of metal alloys which can be processed.

Barocal is developing a zero global warming potential (GWP) alternative to fluid refrigerants, harnessing the barocaloric effect (BCE) in solid refrigerants, where materials undergo large thermal changes on application and removal of pressure to develop cooling and heating systems.

BKwai is developing machine learning based solutions that enable smarter construction and asset monitoring, by turning big data into engineering intelligence. BKwai spun-out of the University of Cambridge in 2019.

Bumblebee Power Limited (Bumblebee) is developing next generation inductive power transfer technology for the wireless recharging of a wide variety of battery-powered devices and vehicles. Bumblebee’s lightweight solution provides a large area in which to position the vehicle to be charged relative to the charging pad, as well as the capability to charge multiple vehicles

OW Smell Made Digital, a UCL and University of Sussex spin-out previously known as OWidgets, has developed technologies that enable the digitisation and commercial exploitation of the human sense of smell. It is a unique and defensible platform technology that provides a unique capability to design, deliver and evaluate smell sensations and the impact these

Zetta Genomics is exploiting unique big data technology for the storage and management of genomic data. Advances in genomics including next generation sequencing are driving changes and innovation in healthcare. Despite the potential, ineffective data management of these complex and large data sets has restricted utility. Zetta has developed a system with the appropriate scale

Carbon Re is a University of Cambridge and UCL spin-out, which has developed AI-powered process optimisation software to enable energy efficiency and emission reduction in process industries. Carbon Re’s proprietary software platform, Delta Zero, uses deep reinforcement learning to enable reductions in energy consumption, cost and carbon emissions.

Cheesecake Energy Limited (CEL) is developing a green energy storage technology known as eTanker that stores electricity in the form of compressed air and heat. eTanker is deployed in a modular, containerised package, making it suitable for a range of terrains and applications in industry including local renewable microgrids, electric vehicle fleet charging and heavy industry.

Helio is commercialising perovskite materials in light-emitting applications such as display panels, whether LCD, OLED or μLED. Perovskites are of strong interest as they are highly efficient and tuneable emitters of pure light. This enables increased brightness, colour range and power efficiency. Helio is a joint spin-out from Oxford and Cambridge Universities and will initially

Bonnet is developing a SaaS platform for chargepoint operators (CPOs) and fleets, and a mobile application for EV users to provide reliable, interoperable, and cheap access to a wide range of chargers for users of EV vehicles, both personal and corporate. There are over 50 different charging networks in the UK with unique payment systems,

FreshCheck has developed a novel colour change technology to detect bacterial contamination on surfaces. Surface testing technology is required across many industries, and the existing technology is unreliable, slow and expensive. FreshCheck’s technology is affordable, simple, gives rapid and reliable results and can be applied across a wide range of products.

VersedAI, a University of Cambridge spin-out, is developing an advanced supervised deep learning solution that will allow companies to better understand significant business risk associated with their supply chains. The company’s technology uses advanced supervised deep learning methods combined with VersedAI’s own proprietary training data set to extract supply chain information from unstruct

Carbometrics is a specialist supramolecular chemistry company. Carbometrics’ core technology is a synthetic molecule that was intricately designed to bind to glucose – A Glucose Binding Molecule (GBM) – which is being used to develop a new glucose sensor chemistry that can help patients manage diabetes, via Continuous Glucose Monitors (CGM).

Machine Discovery is an Oxford University spinout delivering a platform for optimisation, advanced statistical inference, and massive acceleration of computational simulations. The company leverages neural networks technology to replicate and accelerate simulations, thereby obtaining results many orders of magnitude faster than conventional simulation tools.

HexagonFab is developing a novel approach for process monitoring in the biopharmaceutical industry. The company has developed a portable and affordable instrument: ‘HexagonFab Bolt’, which can very rapidly generate biopharmaceutical data.

TextMine (previously known as Legislate) provides AI powered data extraction. The company has developed a range of products that make business-critical documents, including invoices, payslips, and contracts, machine-readable using AI and knowledge graphs. Its first product, Legislate, enables a new category of smart, open contracts which know what they contain and how they connect with

iKVA can index very unstructured data from both internal and external sources and across multiple languages including documents, chat and video and bring all this information together in one place.  iKVA ’s technology is founded on research from Cambridge University’s Computer Lab with many of the prime researchers coming together to form the iKVA team.

GripAble is developing an ecosystem of sensor-based devices and a software/data platform to replicate hospital rehabilitation therapy for in-home settings and hence to deliver improved clinical outcomes.   GripAble was a spin out from the Department of Medicine and Department of Bioengineering at Imperial College. The company is developing home-based treatment rehabilitation, with the first

Zentraxa is developing and bringing to market a range of high-performance biomaterials.  Early applications of its de-bondable adhesive technology are in the areas of advanced wound care and security. 

Charco Neurotech are developing a non-invasive vibrating device called CUE1, to help manage Parkinson’s symptoms. CUE1, a non-invasive wearable device for Parkinson’s, utilises pulsed cueing and focused vibrotactile stimulation to reduce symptoms of slowness and stiffness resulting in improved movement.

Riverlane is a world leading quantum engineering company, on a mission to make quantum computing useful, sooner. Riverlane is comprehensively addressing the challenge of quantum error correction, by building Deltaflow.OS – the operating system for error-corrected quantum computers.

NoBACZ are pioneering a precision bandage platform to revolutionise wound care management. Their wound care products are sterile, antimicrobial, and biodegradable and can be tailored to suit any wound type.

1715 Labs is a data labelling platform that allows AI to reach its full potential by structuring the data so that it can be effectively and efficiently analysed

Nyobolt (formerly called CB2 Tech) has developed a proprietary process using niobium-based anode materials to create batteries that deliver record high power, ultrafast charge and high energy. The world-leading charge and discharge rate capability of Nyobolt batteries, extensively recorded in academic journals, presents a huge opportunity to supercharge the electric revolution. The batteries also

Nu Quantum make quantum devices which can emit and detect single-photons

GaitQ’s product the gaitQ system, a wearable, smart medical device, is looking to improve the lives of people living with Parkinson’s. The company are conducting early-stage consumer usability tests to inform the design of a reliant, discreet, and user-friendly wearable gait measurement device.

Ceryx Medical are a pioneering company in the emerging field of bioelectronic medicine. Spun out from the Universities of Bath and Bristol in 2016 following successful joint scientific research programmes, Ceryx Medical is developing a unique bioelectronic technology which can mimic nerve centres within the body called Central Pattern Generators (CPGs). These CPGs help to

PharmEnable is a drug discovery company using advanced medicinal chemistry and AI approaches to develop highly complex and specific drug candidate molecules

Xampla is developing a novel class of plant-protein materials which provide natural alternatives to plastics. These materials can be manufactured in a wide variety of forms, including films, threads, gels and microbeads, and all have a high degree of biodegradability.

Kalium Health is developing the world’s first blood electrolyte tests for home use. The first product will be a hand-held reader, similar to a blood glucose monitor, and single-use, disposable electrolyte (potassium initially) sensing test strips which respond to a finger-prick blood sample.

Cambridge Photon Technology (‘CPT’) is developing photon multiplier film technology, which increases the power output of silicon photovoltaic products significantly.

DIOSynVax (Digitally designed, Immune Optimised Selected and Synthesized Vaccines) is developing a new technology that will significantly accelerate vaccine development and achieve dramatic improvements to the protection against emerging and re-emerging pathogens.

RoboK have developed sensing algorithms for low-power computing platforms for use in advanced autonomous mobility and the IIoT.

Entia, a spin-out from Imperial College London, have developed an accurate blood test from a simple finger prick. Entia is developing the Aptus, for haematocrit and haemoglobin measurement, and the Affinity, for cancer patients to monitor blood counts at home.

Based on research developed in Professor Rachel Oliver’s lab in energy transitions research, Poro Tech is developing a disruptive substrate platform to help commercialise the GaN revolution.Initial target markets include LED and power electronics.

Hone Bio (previously Cytoseek) has developed a novel cell membrane augmentation technology, enabling the addition of new functionalities to cell therapies including tissue specific targeting and enhanced cell survivability. A spin-out from the University of Bristol, Hone Bio’s technology is based on the research of Dr Adam Perriman, who pioneered a new methodology for the

Mogrify has developed a systematic big data-science approach powered by next-generation sequencing and gene-regulatory data to identify the optimal combination of transcription factors (in vitro) or small molecules (in vivo), needed to convert any mature cell type into any other mature cell type without going through a pluripotent stem cell.

Industrial Phycology (I-Phyc), a member of Bristol’s SETSquared technology incubator, which has developed a patented process that allows microalgae to be used consistently year-round for sustainable, chemical free treatment of process and wastewaters and the recovery and reuse of valuable materials they contain. I-Phyc has developed an advanced, modular, weather independent and containerised pro

Lumenisity is a University of Southampton spin-out, which has developed patented, innovative hollowcore optical fibres promising significantly superior speed and data capacity compared to existing communication fibres. Higher speeds and increased capacity make the Lumenisity hollowcore fibre a good fit with Data Telecom markets requiring high performance, where there is significant market potentia

Echopoint Medical Limited is a University College London (UCL) spin-out, which has developed core photonic sensor technology to greatly enhance the diagnosis and treatment of coronary heart disease. Echopoint was founded upon the research of Dr Adrien Desjardins, Dr Malcolm Finlay, Dr Ioannis Papakonstantinou and Dr Richard Colchester. The core research has attracted grants totalling

PolyProx Therapeutics is a spin out of the Department of Pharmacology at the University of Cambridge,  and is based on over a decade of research and intellectual property from Founder, Professor Laura Itzhaki’s laboratory. Professor Itzhaki is joined at PolyProx Therapeutics by serial Cambridge biotech entrepreneurs Kevin Moulder as Chief Operating Officer and Andrew Sandham

Cambridge GaN Devices (CGD) is a spin out from the High Voltage Microelectronics and Sensors lab at the University of Cambridge Engineering Department. The lab has a successful track record of commercialising innovation and one of the founders, Florin Udrea, was behind the success of Cambridge CMOS Sensors; a Cambridge spin out in an adjacent

QKine spun-out from the  University of Cambridge in 2016. The company manufactures high quality growth factors and cytokines for stem cell, organoid and regenerative medicine applications. QKine uses proprietary protein purification and engineering technology to make recombinant proteins in E.coli. 

Oxford Brain Diagnostics is the result of an 8-year collaboration between Professor Steven Chance (neuroscience and pathology) and Professor Mark Jenkinson (brain imaging), and has resulted in the development of the Cortical Disarray Measurement (CDM), a novel approach that uses MRI scans to provide an index of the health of the cellular circuits in patients’

Phasecraft was established to develop quantum software for quantum information processors encompassing both near-term intermediate-scale devices and universal fault-tolerant computers. Phasecraft aims to enable early stage quantum computers to deliver practical results through the use of their specialist software.

PetMedix is utilising tried and tested antibody technology to develop treatments for diseases in companion animals. Monoclonal antibodies are now a hugely important human drug class but are in their infancy in the treatment of animals. PetMedix will take tried and tested techniques and apply them to the treatment of dogs and cats.

Flusso have developed flow sensors built utilising CMOS MEMS technology allowing for very small form factor, low cost, high performance fluid flow sensors, founded by successful serial entrepreneur academic also behind CCMOSS.

Istesso is a drug discovery and development company working in the field of immunometabolism. Its products work by reprogramming cellular metabolism and have applications in autoimmune conditions such as rheumatoid arthritis and multiple sclerosis, as well as cancer.

Echion Technologies is developing a portfolio of advanced battery active materials, a key battery component with a major impact on battery performance. The company is engaging with chemicals and battery cell manufacturers to integrate its materials solutions into their next-generation products. Echion Technologies provides a unique platform for battery material and composite ma

Duel is a centralised software hub for managing brand ambassador programs and all aspects of customer advocacy

Ikarovec was formed to commercialise certain orphan assets from Quethera, a spin-out from the University of Cambridge, which was acquired by Astellas Pharma Inc. Initially Ikarovec is working on early stage assets intended for the treatment of diabetic macular edama.

Vitamica is using optical technology from the School of Physics at the University of Bristol to commercialise a rapid diagnostic method for bacterial infections. The technology, Sub-Cellular Fluctuation Imaging, detects nanoscale fluctuations, that are present when bacteria are alive, in real time.

AudioTelligence has developed algorithms which are embedded within consumer devices and which transform the clarity and intelligibility of the audio to and from those devices. This allows the devices – home assistants, smart speakers, automotive products, hearing assistance devices, communications systems, and many more – to be used in real world situations where there is

Oxa is an autonomous vehicle software company whose technology operates in any location with zero dependence on external systems i.e. no GPS and no third-party maps. Its autonomous control system, Selenium, is a suite of software that combines data from vehicle sensors to drive autonomous vehicles. The Company’s cloud-based fleet management system, Caesium, schedules and

LettUs Grow designs irrigation and control technology for vertical farms that makes them simple, efficient and sustainable. The company supplies aeroponic hardware, to grow plants in an air/mist environment without soil, and software and data services to optimise performance for individual plant species.

Refeyn is a spinout from the Kukura group at the University of Oxford which has designed the world’s most sensitive light microscope. Their new approach is based on detecting light scattered by single molecules to generate a high-quality movie of single biomolecules as they approach the surface of a glass slide. The molecular mass of

Bramble Energy is a University College London and Imperial College London spinout which has developed a unique, patent protected, printed circuit board (PCB) fuel cell -the “PCBFC”. The PCBFC utilises standardised cost-effective production methods and materials from the PCB industry to reduce the cost and complexity of manufacturing hydrogen fuel cells. Bramble Energy’s ability to

Undo.ai has created a proprietary highly-optimised JIT translation engine that can record the execution of a program completely, perfectly, and efficiently. The resulting recording can be analysed to extract any detail of the program’s execution: every line of code that executed and every memory location at any point in its execution history. This is done

Sorex Sensors utilises high sensitivity MEMS mass sensors, based on film bulk acoustic resonator technology, which resonate at different frequencies when mass attaches to the surface. Hence extremely accurate mass measurements can be made. These sensors are suited to applications where small masses e.g. 10-15g require detection in devices with extremely small form factors. 

Nozzle (previously Mediagamma) has world class AI technology and is focused on computational advertising. It utilises AI technology to help advertisers optimise against metrics such as Customer Acquisition Cost (CAC) and Lifetime Value (LTV), by finding audiences and engaging with them; and publishers to optimise revenue and yield, by building audiences and monetising them. This

Oxford Flow designs and manufactures innovative pressure control equipment. There has been little innovation in this field over many years and Oxford Flow’s pressure reducing valves and gas pressure regulators are smaller and lighter with less moving parts than competing technology. The technology can significantly reduce costs for energy, water and process industries.

OxSyBio is developing technology that could allow 3-dimensional printing of living tissues that display the basic behaviours and physiology of natural organisms. The technology was originally conceived by Professor Hagan Bayley, who founded Oxford Nanopore. Its potential uses vary from printing reference cells to test pharmaceutical products all the way to artificial organs.

Ditto’s platform technology allows companies to automate decision-making in a way that is accountable, transparent and ethical. The company provides artificial intelligence to organisations operating in regulated, safety-critical and error-intolerant environments. The explainable AI interface doesn’t just give answers, it also shows how it reached a conclusion, with the reasons laid out in pla

Dynamic Vision Systems builds electronics on curved surfaces. The company brings leading expertise in liquid crystals, novel manufacturing and ophthalmology / optometry together to create smart contact lenses.

Utilising ultrafast pulsed lasers and world-leading adaptive optics research, Opsydia is set to disrupt a number of industries by its ability to create practically invisible structures inside transparent materials. Permanent and inimitable serial numbers, images or cryptographic data can be laser-written without compromising the integrity of the material or modifying its surface. Material applicat

Quantum Motion Technology is developing a revolutionary technology platform using a scalable array of qubits to create quantum computing architectures that are compatible with standard silicon processing.  By creating a scalable quantum computing technology the Company will be able to tackle currently intractable problems in fields as diverse as chemistry, medicine and artifici

MOA is a plant genetics company using its proprietary technology to generate potential candidates for use as herbicides. The herbicide market mirrors the antibiotic market, in that there have been few new molecules developed in recent years and resistance is developing to those products on the market.

NeoPhore targets the dynamics of cancer neoantigen evolution and aims to make effective, well-tolerated medicines that will become a key part of the next-generation of cancer immunotherapies. NeoPhore’s drugs are designed to stimulate immunity directly at cancer’s core, by interfering with DNA repair and forcing cancer to continuously produce neoantigens that will be detected by

Paragraf has developed a method to manufacture two-dimensional materials, for example graphene, in highly uniform properties, contamination-free form at wafer scale using MOCVD. Graphene has many potential uses given its properties as highly conductive, highly transparent and very strong.

Intelligent Ultrasound is a global supplier of advanced ultrasound training simulators and education. Its products range from virtual reality simulation to online e-learning and hands-on courses. The technology could one day enable consumers to scan themselves at home, through AI enabled hardware and diagnostic apps on their cell phones.

Ionix Advanced Technologies has developed ultrasonic transducers designed from the ground up to operate continuously in extreme environments across a range of industries. The Ionix novel and proprietary piezoelectric technology offers reliable, stable and cost effective ultrasonic measurements at temperatures from –40°C up to +380°C and in the presence of ionizing radiation.

OQC’s mission is to put quantum in the hands of humanity, to solve some of the world’s most challenging problems. They have built the most advanced and only commercially available quantum computer in the UK and achieved performance parameters as good as or better than key competitors at a fraction of the cost.

Inkpath has developed the first comprehensive, data-driven software platform to help users plan and track their skills and career development. A smartphone app and database helps users and their organisations by providing rich, live dynamic data. Deployed primarily within universities, the platform is about people performance as well as course performance and aims to disrupt

Inductosense has developed compact, wireless systems for fast, repeatable detection of cracks, corrosion or defects in structures or products. The ultrasonic sensors are not powered so can be attached to structures in remote places and under coatings, for example. The detectors activate the sensor through inductive coupling.

Cycle.land initially focused a peer-to-peer bike sharing platform which made it easy for anyone to share their bikes with one another. The company is now working with global companies such as OFO and Mobike to launch and manage large-scale bikeshare schemes across multiple cities. Cycle.land believe the future is about flexible fleets and data driven

Creavo has developed diagnostic technology using magnetocardiography (MCG) to measure fluctuations in magnetic fields caused by heart activity. The first product resulting from the work will help physicians in A&E departments rule out significant heart disease in patients presenting with chest pains. This represents a considerable portion of A&E patients but existing protocols take up

Predictimmune is a molecular diagnostics company whose core IP predicts long-term disease outcome in immune-related diseases. The issue is that immune diseases are characterised by a high degree of disease heterogeneity and treatment is associated with high costs and severe side effects. Hence some patients may need aggressive treatment early and others may need to

The company is developing novel, easy-to-use and affordable ophthalmic instruments utilising polarised light technology. The first focus is on screening people for low macular pigment density, which is an early predictor of age-related macular degeneration (AMD). AMD is a serious problem for upwards of 150m people worldwide and it cannot be cured. There are simple

NuNano specialises in the design and manufacture of probes for atomic force microscopy (AFM) and cantilever-based sensor devices. Its proprietary microfabrication processes enables it to manufacture AFM probes with the tightest dimensional tolerances in the market.

Congenica has translated research from the Sanger Institute, based on ground breaking research from the Deciphering Developmental Disorders Study, which collected genetic data from 40,000+ people at 24 NHS labs into a clinical genomics analytical platform, called Sapienta. Congenica’s software will enable the accurate, rapid and scalable clinical interpretation of genetic and clinical data,

Bibliu (formerly Bibliotech) provides broad textbook content through an online subscription offering that offers students enhanced search, annotation and other services. This addresses the problem of the high cost of textbooks and the limited availability and restricted use of textbooks from libraries. The Bibliu platform also allows universities, departments, libraries and publishers to monitor u

Covatic is developing a decision engine to enable a unique, personalised television and radio experience. The technology incorporates linked data and semantic reasoning. Currently content is largely still delivered on a “by appointment” basis and data is generated, via Nielsen or BARB, post transmission. Covatic offers a decision engine that will select the most appropriate

Focal Point Positioning has developed software which offers highly accurate positioning information for smartphones both indoors and outdoors in urban areas. Locating people or objects using existing technology is problematic in such spaces but the team’s work on systems as diverse as submarines and Martian rovers has given them a technological edge in the field.

Polypharmakos is a collaboration between the Royal Botanic Gardens, Kew and Cambridge. The company is utilising Kew’s unrivalled expertise in plants and fungi to seek new antimicrobial mechanisms for drugs. It is also looking at invertebrates as a source of potential antimicrobial activity with the Universities of Swansea, Oxford and Cambridge.

Mode is exploiting the electrochemical properties of biomarkers to produce novel assays for home diagnostic purposes. The company has developed a suite of technologies comprising assay development techniques, biosensing capabilities, microfabrication, electronics and wireless communications. Mode’s first product represents an evolution in bowel cancer screening, offering significant improvements

Exonate has proprietary mRNA splicing technology and specialises in altering angiogenesis, the formation of new blood vessels. Its first programme, in conjunction with the University of New South Wales in Australia, has a lead candidate for wet age-related macular degeneration. The product is now in pre-clinical trials.

Proxisense uses proprietary eddy current sensors and custom algorithms to provide highly accurate positioning data for extreme and inaccessible mechanical environments. Such measurements provide comprehensive health monitoring for engines, reducing whole life cycle costs by detecting degrading performance and predicting potential failures. 

Ilika is a materials company which is focusing on its solid state battery technology. Its proprietary anode material and manufacturing know-how enable it to construct safe and efficient batteries with a very small footprint. These are suitable for powering devices used in the Internet of Things and wearables, e.g. medical devices. Ilika has a pipeline

An Imperial College spinout, Ceres Power has developed low cost, steel fuel cells that operate on mains natural gas. The cells can be manufactured using standard steel and ceramic products and standard industrial processes. The high efficiency of the cells keeps cost down and reduces the carbon footprint of energy production. The flexibility of the

Healthera has developed an app that enables patients to use the power of their mobile device to monitor and schedule their medicine use, and to stay in contact with their local pharmacy for advice and other services. The app can also be used by carers to monitor other people &/or animals. For pharmacies it enables

PervasID provides unique, passive radio frequency identification (RFID) solutions with unrivalled detection capability and enables sophisticated IoT infrastructures. The technology outperforms current passive technologies and is cheaper but as accurate as active RFID systems. PervasID’s unique passive RFID tag reader technology for retail, healthcare and security sectors tracks items, increases

Micrima has developed the MARIA breast cancer detection system to identify and locate lesions in breast tissue. The system exploits permittivity differences using radio waves and as a result is fast, safe and inexpensive. It should also generate more effective screening for women with dense breast tissue, an area where the existing technology, X-ray mammography,

Psyomics has utilised its experience from University labs and the Delta clinical trial to create a digital mental health assessment tool called Censeo. Censeo delivers a psychiatrist quality mental health assessment to help reduce misdiagnosis and get patients on the correct treatment pathway quicker, whilst improving GP and psychiatry efficiency. 

8power specialises in self-powered wireless sensor solutions for industrial plant applications. Its Vibration Energy Harvester (VEH) technology provides self-powered wireless sensors that eliminate battery changes or wiring of power supplies. 8power’s technology provides a proactive, early warning and remote monitoring solution for a range of industrial plant equipment.

Inflowmatix is an Imperial College London spin-out that has developed sensor technology to detect high frequency, transient pressure events in water systems together with and advanced data visualisation and analytics platform. The technology enables water network operators to control pressures and optimise their services including resilience, asset management, leakage and water quality in order to

Cambridge Touch has developed next-generation 3D multi-touch technology for next generation smart devices. CTT uses a combination of a proprietary AI engine running unique signal processing algorithms, and a specialized Piezoelectric Force Film, to enable the world’s simplest sensor architecture that delivers superior functionality at lower cost, and scales to all device sizes and shapes.

Spectral Edge leads the world in Image Fusion  technology. Combining its Image Fusion IP with Machine Learning reveals more of the colour, detail and clarity in a scene to enhance pictures and videos produced by mass market devices. Applications range from enhancing photographic images, and improving security surveillance, to enhanced visual accessibility for colour blind

Mind Foundry’s AI and Machine Learning platform will build the systems of intelligence that allow organisations to create new opportunities, optimise complex decisions and generate better outcomes. The platform allows organisations to leverage their existing investment in technology, future-proofing their business models with state-of-the-art operational machine learning helping them help them t

Zegami has developed software that provides the capability to manage and sort collections of images and data visually. It allows users to view very large collections of images and associated metadata in a single view and to search, sort, filter and group them in real time. 

Silicon Microgravity is developing the world’s smallest high performance MEMS-based microgravity sensor with a projected resolution of approximately one billionth of the Earth’s gravity. This technology has applications in fields as diverse as Carbon Capture and Storage, the oil and gas industry, ground water management, civil and mining engineering and the defence and space industries.

Oxford Endovascular is developing next-generation medical devices for neurovascular disease. The Company’s sophisticated metallic mesh tube devices and systems can be used to treat patients suffering from brain aneurysms. The tubes are made from a special metal alloy which has a shape memory and unfolds in the blood vessel when in place. The product and

A spinout from the University of Oxford’s Department of Zoology, Animal Dynamics will build bio-inspired vehicles mimicking animal motion in robotic devices, miniature drones and autonomous small freight transports. In March 2019 we sold the UOIF II holding via a secondary sale generating a multiple return for investors.

Built on novel algorithms developed at the University of Oxford, Navetas’ Loop Energy Saver system uniquely tracks electricity and gas use in the home, so consumers know in real time what energy they are using and the cost. The Loop Energy Saver platform automatically tracks energy consumption against all the best tariffs on the market and

Bodle has developed a novel display technology using solid state phase change materials that can be used in low-energy, high resolution displays with significantly better readability than existing backlit displays.

BOXARR solves the increasingly challenging and costly problem of complexity in the Aerospace and Defence industry. It is an innovative software application that efficiently increases understanding of complex networks of dependency, enabling visibility and control in high-value and highly-complex business domains, such as Systems Engineering, Supply-Chain Management and Product Development Processe

GeoSpock provides a real-time scalable database for rapidly changing complex data.  The company’s ambition is to become the Google Search of Big Data. GeoSpock’s technology platform sits at the base of an infinite number of Industry verticals which require real-time analysis of Big Data and all that confers in affiance and accuracy for any number

Cytora has developed technology which can detect factual, real world events from unstructured text. It can deliver this in real time which has transformed underwriting for commercial insurance. The Cytora Risk Engine uses artificial intelligence to learn the patterns of risks over time, enabling insurers to improve profitability and deliver fairer prices to their customers.

Xerion Healthcare has developed nanoparticles specifically to increase the effectiveness of cancer treatments. The particles, which are titanium dioxide-based, are injected into tumours prior to standard radiotherapy and amplify the dose of free radicals generated by the X-rays. Initial targets for the technology are head and neck and pancreatic cancers.

Quethera is a gene therapy company developing a novel treatment for glaucoma. The company targeted delivering gene products for neuroprotectants and their receptors directly to the eye. This could provide long term neuroprotection to the retinal ganglion cells (RGC) in the eye, preventing their death and visual field loss.

Orthox is a medical device company founded in 2008 to exploit FibroFix, a novel silk-based biomaterial platform, for the repair of injuries to cartilage and bone. FibroFix combines exceptional strength and resilience with a porous architecture and chemical structure similar to Fibronectin, an essential component of human cartilage.

Reduse seeks to change the way laser printed office paper is treated post use. Instead of disposal, recycling or shredding the ‘unprinter’ technology could clean off all toner without damaging the paper. Carrying out delivery, storage and control of waste paper takes time; and the costs of secure shredding and footprint are significant.

Active Inspiration developed a mobile health and exercise wearable app that uses industry standard secure protocols to allow members to collect all their exercise data in one place.  Members can choose to connect their preferred exercise apps like Fitbit, Garmin or Strava to their Bounts account to earn points and credits.

Mirriad is a computer vision and AI-powered platform company, delivering in-video advertising by naturally blending brand advertising into popular entertainment content. Using sophisticated technologies, Mirriad connects people with brands, through seamless ad insertions in popular linear and digital content. Advertisers can now reach very large target audiences in a contextually relevant way with

Cisiv is a pioneering developer of technology solutions for pharmaceutical companies, enabling customers to capture new levels of information on the use of their products and treatments in real world settings. Cisiv’s next generation web-based software platform enables pharmaceutical customers to capture, analyse and share phase IV (post approval) observational study patient data quickly, simply

Sphere Medical is a dynamic medtech company currently developing a series of innovative critical care devices from its sterile, miniaturised, electrochemical sensor technology platform. The first product, Proxima, is the only patient-connected, continuous blood gas analyser offering vital clinical information quicker, more frequently, and at the bedside providing efficiencies that result in reduce

PhoreMost has developed a next-generation phenotypic screening platform called ‘Site-Seeker’ to identify the best new targets for future therapy, and crucially, how to drug them. This has the potential to significantly increase the diversity of novel therapeutics for cancer and other unmet diseases, where treatment options are currently severely limited.

Fluidic Analytics is developing a line of tools for the rapid, accurate, cost-effective analysis of proteins and other biomolecular species. By combining a powerful microfluidics platform with efficient manufacturing and design principles, the Company is striving to be a leading provider of products that enable breakthrough advances in fundamental protein science, drug development and diagnostics.

TheySay developed academic research in computational linguistics from the University of Oxford. The company generated sentiment analysis technology and tools.

Salunda develops robust condition monitoring solutions for oilfield machinery, drilling and metering. The products are non-invasive, contactless and have no moving parts to enable them to operate in harsh environments. Products include the Latch Hawk pipe handling safety monitors and MudChecker drilling fluid analyser.

Nandi Proteins is leading the way in protein technology for commercial use in the food and drink sector. The Company is a market leader in developing technology and scientific expertise to improve the functional properties of proteins in food manufacturing and nutrition.

Perpetuum engineered, produced and commercialized the world’s first practical electromagnetic vibration harvesting micro-generator. The device delivers the power required to transmit large amounts of autonomous wireless sensor data reliably from remotely monitored assets. Perpetuum’s self-powered, wireless sensing technology, combined with vibration engineering expertise and rich analytics pro

Brainomix is aiming to improve stroke treatment dramatically by developing systems that gives all hospitals and clinics access to reliable diagnoses for their patients. The Brainomix e-ASPECTS platform is first system in the world to provide automated, standardised analysis of CT brain scans for stroke damage, assessing patients’ suitability for life saving treatment.

Oxtex is an early-stage medical device company which has developed a novel self-inflating tissue expander for the use in reconstructive surgery. The device is implanted underneath the skin close to the repair site, where it will slowly expand in one direction causing the skin to grow which can then be used in the reconstruction.

ROADMap is a pioneering technology company in the field of optical telecommunication and data communication switching. The Company is developing unique and novel technology in wavelength selective switches (WSSs). These switches are currently used to create reconfigurable optical add/drop multiplexers (ROADMs) which are now a fast growing part of the optical network where they enable

Jukedeck is based on state-of-the-art technology that brings artificial intelligence to music composition and production. The Company is training deep neural networks to understand music composition at a granular level, building tools to aid creativity.

VocalIQ exploited technology developed by the Spoken Dialogue Systems Group at University of Cambridge. The technology has wide applicability for automated spoken language interfaces, including smartphones, smart speakers, robots, cars, call-centres, and games. In September 2015 VocalIQ was acquired by a leading US consumer electronics company.

Fuel 3D has developed proprietary algorithms, software and 3D hardware platforms that deliver extremely high quality 3D shape and colour capture for a range of retail and pharmaceutical applications. The Fuel3D Biovolume scanner is a point-and-shoot 3D scanning system that accurately captures and reconstructs 3D tumour surface changes, enabling the analysis of texture, colour, shape

Aqdot is a supramolecular chemistry company with a with a novel and versatile technology that t has exceptional capability at capturing, holding and releasing materials. In unique and proprietary formulations, this chemistry is game-changing in a wide range of industries, including household and personal care products, fragrances, industrial chemicals, agrochemicals, and pharmaceuticals.

Cloud Sustainability is a cloud based software platform that changes the way sustainability knowledge, consultancy and training is delivered. It reduces costs, educates and empowers the user, creating self-sufficiency and delivering long-term sustainable benefit.

Symetrica specializes in the detection and identification of radioisotopes for Security Applications. The company works with prime contractors and government agencies to design, develop, test and deploy detection equipment for use by law enforcement personnel, customs officers, the emergency services, military personnel and first responders.

Omega Diagnostics is focused on selling a wide range of specialist products, primarily in the immunoassay, in-vitro diagnostics (IVD) market within three segments: Allergy, Health & Wellbeing and Global Health.

Through the use of gene editing and gene modulation technologies, Horizon provides a wide range of products and services to customers across the life sciences based on the development of cell-based models and their application. Horizon’s powerful gene editing platform develops genetically engineered cell models which are used to understand the role of genomics in

Microsaic is the first, and only company to have successfully miniaturised mass spectrometry through the development of its patented chip-based technologies based on Micro-Electrical-Mechanical Systems (MEMS). This chip-based mass spectrometry technology enables point-of-need detection at any stage in a user’s workflow and allows pharmaceutical and biopharmaceutical industries to achieve process

Tangentix is dedicated to providing the best possible computer game delivery experience. It uses proprietary and patented technologies to compress game assets so a typical title is significantly reduced in size, making downloads possible for nearly all internet users. It also has sophisticated Digital Rights Management, which allows game publishers to control and manage the

Sphere Fluidics picodroplet technology makes it possible to encapsulate and screen millions of individual cells or biological molecules in a single day. Its CytoMine proprietary microfluidic technology allows the ultra-high throughput analysis of isolated cells and generation of their genetic, transcriptomic and proteomic profiles in miniaturised (pL to nL) picodroplets. 

DefiniGEN provides human cells to the life science and drug discovery sectors for use in lead optimization and toxicity programmes. DefiniGEN’s proprietary production platform OptiDIFF robustly generates human cell types including liver hepatocytes using hIPSC human Induced Pluripotent Stem Cell technology.

Clean Air Power pioneered its innovative Dual Fuel™ technology and complementary component systems guarantee diesel engine performance and delivers lower fuel costs for operators and performance for drivers, with the added benefit of lower CO2 emissions.

Inotec AMD is a wound-care company that has developed Natrox™, a device that produces a continuous flow of humidified oxygen and directs it to a specially-designed dressing, allowing oxygen to constantly refresh the wound while allowing free passage of wound fluids (exudate) to pass away from the wound surface for absorption and retention in the normal

Cambridge CMOS Sensors is the provider of innovative MEMS high temperature micro hotplate technology for gas sensing, flow sensing and lab-on-a-chip applications. The Cambridge CMOS Sensors technology uses standard CMOS processes that enable high volume, low cost and low power sensor-on-chip solutions. Cambridge CMOS Sensors have created the world’s smallest gas sensor for consumer applications.

YASA has developed revolutionary compact, lightweight and powerful electric motors and controllers. The products enable vehicle hybridization and electrification, especially where there is limited powertrain space. The company supplies custom and off-the-shelf e-motors and controllers to automotive customers from its Oxford headquarters.

Arkivum has developed a permanent long-term data management process to manage data security and safety. The Arkivum platform delivers long-term preservation and safeguarding of some of the world’s most prestigious and important data. Built-in automated processes ensure future accessibility, easy search and usability of data, making content discoverable and available over any digital channel.

Arvia offers a unique solution for the reduction of hard-to-treat organics, micropollutants and colour from water and wastewater streams. The technology removes and destroys organic contaminants and oils using a method that is free of process chemicals, is energy efficient, and produces little solid or liquid waste for disposal. Applicable to water treatment and purification

Surrey NanoSystems has developed technologies that deliver precise, ordered nanomaterial structures for advanced CMOS manufacturing processes at low temperatures. Using this technology, the Company developed super-black coatings, including Vantablack®. Vantablack® is revolutionary in its ability to be applied to light-weight, temperature-sensitive structures, whilst absorbing 99.96% of incident

Reinnervate’s ALvetex platform is a unique scaffold that enables routine 3D cell culture in the lab. By enabling cells to grow in a 3D environment, Alvetex better mimics the conditions experienced by cells when growing in normal tissue. The technology provides a flexible platform that allows technicians to quickly and easily establish better in vitro assays and

Lime Microsystems pioneered the creation of the single chip transceiver and now specialises in field programmable RF (FPRF) transceivers, SDR solutions, IoT gateways and mobile base stations for the next generation of wireless broadband systems.

First Light Fusion is researching energy generation by inertial confinement fusion. First Light’s work to-date has included theoretical analysis, detailed numerical simulation and experimental validation. This has allowed description of the accessible parameter space and has led to a clear vision of the pathway to fusion.

Oxford PV has developed technology that produces a combined silicon-perovskite solar cell capable of world record solar energy conversion efficiency. It is manufactured from inexpensive, abundant, non-toxic and non-corrosive organic materials and can be scaled to any volume. The tandem configuration means it occupies the same footprint with greater efficiency, transforming the economics of solar

Tracsis is a developer and aggregator of technology and services that solve mission critical resource management problems within the transportation sector. The company developed software for use in scheduling optimisation and operations planning consultancy businesses. The original IP was built on over 200 man-years of work by researchers at the University of Leeds.

ACAL Energy develops low cost PEM Hydrogen Fuel Cell systems utilising a platinum free liquid catalyst in an attempt to change the future of automotive power trains and stationary power sources.

Itaconix designs and manufactures high performance, cost effective and sustainable ingredients that are key components of products in the personal care, homecare and industrial sectors. The Company is the world leader in developing and producing bio-based polymers from itaconic acid, combining the versatile chemistry of itaconic acid with breakthrough manufacturing economics.

Xeros Technologies developed innovative polymer-based technologies that allow industrial and commercial processes to be carried out using less water. It has built a stand alone commercial laundry business using the technology and has separate operations working in domestic laundry, leather processing, textile finishing and specialist uniform cleaning.

Eykona is 3D hand-held imaging technology for use as a clinical wound measurement and monitoring system. The technology allows clinicians to measure wounds, accurately and repeatably, helping to improve outcomes, reduce costs and ensure that patients with serious wounds are treated optimally.